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Article

Diminished force production and mitochondrial respiratory deficits are strain-dependent myopathies of subacute limb ischemia.

Journal of vascular surgery - 1 May 2017

Schmidt Cameron A, Ryan Terence E, Lin Chien-Te, Inigo Melissa M R, Green Tom D, Brault Jeffrey J, Spangenburg Espen E, McClung Joseph M

Abstract excerpt

OBJECTIVE: Reduced skeletal muscle mitochondrial function might be a contributing mechanism to the myopathy and activity based limitations that typically plague patients with peripheral arterial disease (PAD). We hypothesized that mitochondrial dysfunction, myofiber atrophy, and muscle contractile deficits are inherently determined by the genetic background of regenerating ischemic mouse skeletal muscle, similar...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28024849
DOI: 10.1016/j.jvs.2016.04.041
PMCID: PMC5403600

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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