Article
Genetic architecture underlying variation in extent and remodeling of the collateral circulation.
Circulation research - 20 Aug 2010
Wang Shiliang, Zhang Hua, Dai Xuming, Sealock Robert, Faber James E
Abstract excerpt
RATIONALE: Collaterals are arteriole-to-arteriole anastomoses that connect adjacent arterial trees. They lessen ischemic tissue injury by serving as endogenous bypass vessels when the trunk of 1 tree becomes narrowed by vascular disease. The number and diameter ("extent") of native (preexisting) collaterals, plus their amount of lumen enlargement (growth/remodeling) in occlusive disease, show remarkably wide...
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