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Article

Genetic variation in retinal vascular patterning predicts variation in pial collateral extent and stroke severity.

Angiogenesis - 1 Jan 2015

Prabhakar Pranay, Zhang Hua, Chen De, Faber James E

Abstract excerpt

The presence of a native collateral circulation in tissues lessens injury in occlusive vascular diseases. However, differences in genetic background cause wide variation in collateral number and diameter in mice, resulting in large variation in protection. Indirect estimates of collateral perfusion suggest that wide variation also exists in humans. Unfortunately, methods used to obtain these estimates are...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25369734
DOI: 10.1007/s10456-014-9449-y
PMCID: PMC4422395

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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