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Article

Role of Genetic Variation in Collateral Circulation in the Evolution of Acute Stroke: A Multimodal Magnetic Resonance Imaging Study.

Stroke - 1 Mar 2017

Kao Yu-Chieh Jill, Oyarzabal Esteban A, Zhang Hua, Faber James E, Shih Yen-Yu Ian

Abstract excerpt

BACKGROUND AND PURPOSE: No studies have determined the effect of differences in pial collateral extent (number and diameter), independent of differences in environmental factors and unknown genetic factors, on severity of stroke. We examined ischemic tissue evolution during acute stroke, as measured by magnetic resonance imaging and histology, by comparing 2 congenic mouse strains with otherwise identical genetic...

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Identifiers

PMID: 28188261
DOI: 10.1161/STROKEAHA.116.015878
PMCID: PMC5380467

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