Article
Thymic nurse cells: differentiation of thymocytes within complexes.
Cell and tissue research - 1 Apr 1991
Brelińska R, Seidel H J, Kreja L
Abstract excerpt
Thymic nurse cell complexes (TNC-c) were isolated from thymuses of BDF1 mice at pre-determined intervals during the 12-week latency period that precedes the development of leukemias. T-cell leukemias were induced by a single i.v. injection of 50 mg/kg of methylnitrosourea (MNU). In order to clarify processes taking place in TNC-c, the complexes of mice after MNU injection were compared with TNC-c of age-matched...
Topics
- Animals
- Antigens, Ly
- Cell Differentiation
- Leukemia, T-Cell
- Male
- Methylnitrosourea
- Mice
- Phenotype
- T-Lymphocytes
- Thymus Gland