T-cell reconstitution by molecular, phenotypic, and functional analysis in the thymus, bone marrow, spleen, and blood following split-dose polychemotherapy and therapeutic activity for metastatic breast cancer in mice.

doi:10.1097/00002371-199311000-00002

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Article

T-cell reconstitution by molecular, phenotypic, and functional analysis in the thymus, bone marrow, spleen, and blood following split-dose polychemotherapy and therapeutic activity for metastatic breast cancer in mice.

Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy - 1 Nov 1993

Talmadge J E, Jackson J D, Kelsey L, Borgeson C D, Faltynek C, Perry G A

Abstract excerpt

We examined the effect of a maximum tolerated, split-dose chemotherapy protocol of cyclophosphamide, cisplatin, and 1,3-bis (2-chloroethyl)-1-nitrosourea (BCNU) on neutrophil and lymphocyte subpopulations in the peripheral blood leukocytes (PBLs), thymus, bone marrow, and spleen. It was found tha...

Topics

Animals
Antineoplastic Combined Chemotherapy Protocols
Base Sequence
Bone Marrow Cells
Cytokines
Female
Interleukin-7
Lymphocyte Activation
Mammary Neoplasms, Experimental
Mice
Mice, Inbred BALB C
Molecular Sequence Data
Neoplasm Metastasis

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

RNA

Recombinant Proteins

Spleen

T-Lymphocytes

Source

Open in PubMed

Identifiers

PMID: 7506577
DOI: 10.1097/00002371-199311000-00002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7506577-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.