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Article

Gene expression profile of BRCAness that correlates with responsiveness to chemotherapy and with outcome in patients with epithelial ovarian cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Aug 2010

Konstantinopoulos Panagiotis A, Spentzos Dimitrios, Karlan Beth Y, Taniguchi Toshiyasu, Fountzilas Elena, Francoeur Nancy, Levine Douglas A, Cannistra Stephen A

Abstract excerpt

PURPOSE: To define a gene expression profile of BRCAness that correlates with chemotherapy response and outcome in epithelial ovarian cancer (EOC). METHODS: A publicly available microarray data set including 61 patients with EOC with either sporadic disease or BRCA(1/2) germline mutations was used for development of the BRCAness profile. Correlation with platinum responsiveness was assessed in platinum-sensitive...

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Identifiers

PMID: 20547991
DOI: 10.1200/JCO.2009.27.5719
PMCID: PMC2917311

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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