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Article

Transcriptome Patterns of BRCA1- and BRCA2- Mutated Breast and Ovarian Cancers.

International journal of molecular sciences - 28 Jan 2021

Arakelyan Arsen, Melkonyan Ani, Hakobyan Siras, Boyarskih Uljana, Simonyan Arman, Nersisyan Lilit, Nikoghosyan Maria, Filipenko Maxim, Binder Hans

Abstract excerpt

Mutations in the BRCA1 and BRCA2 genes are known risk factors and drivers of breast and ovarian cancers. So far, few studies have been focused on understanding the differences in transcriptome and functional landscapes associated with the disease (breast vs. ovarian cancers), gene (BRCA1 vs. BRCA2), and mutation type (germline vs. somatic). In this study, we were aimed at systemic evaluation of the association of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33525353
DOI: 10.3390/ijms22031266
PMCID: PMC7865215

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