Article
"BRCAness" syndrome in ovarian cancer: a case-control study describing the clinical features and outcome of patients with epithelial ovarian cancer associated with BRCA1 and BRCA2 mutations.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Dec 2008
Tan David S P, Rothermundt Christian, Thomas Karen, Bancroft Elizabeth, Eeles Rosalind, Shanley Susan, Ardern-Jones Audrey, Norman Andrew, Kaye Stanley B, Gore Martin E
Abstract excerpt
PURPOSE: We evaluated the clinical impact of germ-line BRCA1/2 mutations in patients with epithelial ovarian cancer (EOC) on responses to first and subsequent lines of chemotherapy, treatment-free interval (TFI) between each line of therapy, and overall survival (OS). PATIENTS AND METHODS: Twenty...
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