Article
Phenotypic modulation of human urinary tract stroma-derived fibroblasts by transforming growth factor beta3.
Urology - 1 Aug 2010
Heer Rakesh, Clarke Nick, Rigas Anastasia C, Cheek Timothy R, Pickard Robert, Leung Hing Y
Abstract excerpt
OBJECTIVES: Animal models have described critical roles for transforming growth factor beta (TGFbeta) isoforms in modulating urinary tract stroma phenotype. TGFbeta3 is of particular interest because it may regulate TGFbeta1 and TGFbeta2 expression, but its modulatory affect has not been so well characterized in human cells. In this study, we aim to determine whether TGFbeta3 treatment induced differentiation of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
