Article
Strain history and TGF-β1 induce urinary bladder wall smooth muscle remodeling and elastogenesis.
Biomechanics and modeling in mechanobiology - 1 Jan 2012
Heise Rebecca L, Parekh Aron, Joyce Erinn M, Chancellor Michael B, Sacks Michael S
Abstract excerpt
Mechanical cues that trigger pathological remodeling in smooth muscle tissues remain largely unknown and are thought to be pivotal triggers for strain-induced remodeling. Thus, an understanding of the effects mechanical stimulation is important to elucidate underlying mechanisms of disease states and in the development of methods for smooth muscle tissue regeneration. For example, the urinary bladder wall (UBW)...
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