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Article

Novel regulators of stem cell fates identified by a multivariate phenotype screen of small compounds on human embryonic stem cell colonies.

Stem cell research - 1 Sept 2010

Barbaric Ivana, Gokhale Paul J, Jones Mark, Glen Adam, Baker Duncan, Andrews Peter W

Abstract excerpt

Understanding the complex mechanisms that govern the fate decisions of human embryonic stem cells (hESCs) is fundamental to their use in cell replacement therapies. The progress of dissecting these mechanisms will be facilitated by the availability of robust high-throughput screening assays on hESCs. In this study, we report an image-based high-content assay for detecting compounds that affect hESC survival or...

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PMID: 20542750
DOI: 10.1016/j.scr.2010.04.006

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TRA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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