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Article

High-content screening for chemical modulators of embryonal carcinoma cell differentiation and survival.

Journal of biomolecular screening - 1 Jul 2011

Barbaric Ivana, Jones Mark, Harley David J, Gokhale Paul J, Andrews Peter W

Abstract excerpt

Disentangling the complex interactions that govern stem cell fate choices of self-renewal, differentiation, or death presents a formidable challenge. Image-based phenotype-driven screening meets this challenge by providing means for rapid testing of many small molecules simultaneously. Pluripotent embryonal carcinoma (EC) cells offer a convenient substitute for embryonic stem (ES) cells in such screens because...

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Source

Identifiers

PMID: 21593487
DOI: 10.1177/1087057111406547

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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