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Article

Nrf2 and Keap1 abnormalities in non-small cell lung carcinoma and association with clinicopathologic features.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jul 2010

Solis Luisa M, Behrens Carmen, Dong Wenli, Suraokar Milind, Ozburn Natalie C, Moran Cesar A, Corvalan Alejandro H, Biswal Shyam, Swisher Stephen G, Bekele B Nebiyou, Minna John D, Stewart David J, Wistuba Ignacio I

Abstract excerpt

PURPOSE: To understand the role of nuclear factor erythroid-2-related factor 2 (Nrf2) and Kelch-like ECH-associated protein 1 (Keap1) in non-small cell lung cancer (NSCLC), we studied their expression in a large series of tumors with annotated clinicopathologic data, including response to platinu...

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Identifiers

PMID: 20534738
DOI: 10.1158/1078-0432.CCR-09-3352
PMCID: PMC2920733

Genes

KEAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20534738-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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