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Article

[Role of the expression level of Nrf2 in predicting response of EGFR-TKIs in lung adenocarcinoma patients with EGFR gene mutations].

Zhongguo fei ai za zhi = Chinese journal of lung cancer - 1 Feb 2014

Zhu Xiang, Liang Li, Liu Chen, Yin Wencheng, Chen Sen, Cao Baoshan

Abstract excerpt

BACKGROUND AND OBJECTIVE: Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) have become first-line treatment drugs for lung adenocarcinoma patients with EGFR gene mutations. Significant interindividual variations in response rate, progression-free survival (PFS), and overall survival (OS) have been observed. The expression level of nuclear factor erythroid-2-related factor 2 (Nrf2) is...

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Source

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Identifiers

PMID: 24581168
DOI: 10.3779/j.issn.1009-3419.2014.02.15
PMCID: PMC6000052

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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