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Article

[Nrf2 and Keap1 Abnormalities in 104 Lung Adenocarcinoma Cases and Association with Clinicopathologic Features].

Zhongguo fei ai za zhi = Chinese journal of lung cancer - 20 Mar 2018

Xiao Yu, Zhu Xiang, Gu Yangchun, Chen Sen, Liang Li, Cao Baoshan

Abstract excerpt

BACKGROUND: There are significantly interindividual variations of the expression level of nuclear factor erythroid-2-related factor 2 (Nrf2) and/or Kelch-like ECH-associated protein 1 (Keap1) in our previous studies. It has been proven that Nrf2 or Keap1 is related to resistance of chemotherapeutic drugs and/or epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs). However, the expression of...

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Identifiers

PMID: 29587953
DOI: 10.3779/j.issn.1009-3419.2018.03.04
PMCID: PMC5973043

Genes

EGFR

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