Article
Tracing the origins and signatures of selection of antifolate resistance in island populations of Plasmodium falciparum.
BMC infectious diseases - 9 Jun 2010
Salgueiro Patrícia, Vicente José L, Ferreira Conceição, Teófilo Vânia, Galvão André, do Rosário Virgílio E, Cravo Pedro, Pinto João
Abstract excerpt
BACKGROUND: Resistance of the malaria parasite Plasmodium falciparum to sulfadoxine-pyrimethamine (SP) has evolved worldwide. In the archipelago of São Tomé and Principe (STP), West Africa, although SP resistance is highly prevalent the drug is still in use in particular circumstances. To address...
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