Article
Dynamic changes in genetic diversity, drug resistance mutations, and treatment outcomes of falciparum malaria from the low-transmission to the pre-elimination phase on the islands of São Tomé and Príncipe.
Malaria journal - 14 Dec 2021
Chen Ying-An, Shiu Tsen-Ju, Tseng Lien-Fen, Cheng Chien-Fu, Shih Wei-Liang, de Assunção Carvalho Arlindo Vicente, Tsai Kun-Hsien
Abstract excerpt
BACKGROUND: With effective vector control and case management, substantial progress has been made towards eliminating malaria on the islands of São Tomé and Príncipe (STP). This study assessed the dynamic changes in the genetic diversity of Plasmodium falciparum, the anti-malarial drug resistance mutations, and malaria treatment outcomes between 2010 and 2016 to provide insights for the prevention of malaria...
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