Article
Split hybridisation probes for electrochemical typing of single-nucleotide polymorphisms.
The Analyst - 1 Jan 2009
Lucarelli Fausto, Capponcelli Silvia, Marrazza Giovanna, Sangiorgi Luca, Mascini Marco
Abstract excerpt
This paper describes the development of a highly selective single-nucleotide polymorphisms (SNPs) typing method based on the use of split hybridisation probes and demonstrates the concept through the electrochemical analysis of single-base mutations in actual patient samples. The requirement that...
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