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Article

DISC1 regulates primary cilia that display specific dopamine receptors.

PloS one - 28 May 2010

Marley Aaron, von Zastrow Mark

Abstract excerpt

BACKGROUND: Mutations in the DISC1 gene are strongly associated with major psychiatric syndromes such as schizophrenia. DISC1 encodes a cytoplasmic protein with many potential interaction partners, but its cellular functions remain poorly understood. We identified a role of DISC1 in the cell biology of primary cilia that display disease-relevant dopamine receptors. METHODOLOGY/PRINCIPAL FINDINGS: A GFP-tagged...

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Identifiers

PMID: 20531939
DOI: 10.1371/journal.pone.0010902
PMCID: PMC2878344

Genes

DISC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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