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Article

Apolipoprotein E: far more than a lipid transport protein.

Annual review of genomics and human genetics - 1 Jan 2000

Mahley R W, Rall S C

Abstract excerpt

First recognized as a major determinant in lipoprotein metabolism and cardiovascular disease, apolipoprotein (apo) E has emerged as an important molecule in several biological processes not directly related to its lipid transport function, including Alzheimer's disease and cognitive function, immunoregulation, and possibly even infectious diseases. ApoE is a polymorphic protein arising from three alleles at a...

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Identifiers

PMID: 11701639
DOI: 10.1146/annurev.genom.1.1.507

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