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Article

Comparative transcriptional profiling identifies takeout as a gene that regulates life span

11 May 2010

Abstract excerpt

A major challenge in translating the positive effects of dietary restriction (DR) for the improvement of human health is the development of therapeutic mimics. One approach to finding DR mimics is based upon identification of the proximal effectors of DR life span extension. Whole genome profiling of DR in Drosophila shows a large number of changes in gene expression, making it difficult to establish which...

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PMID: 20519778
DOI: 10.18632/aging.100146

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