Article

Worm Perturb-Seq: massively parallel whole-animal RNAi and RNA-seq

2025-02-03

Abstract excerpt

The transcriptome provides a highly informative molecular phenotype to connect genotype to phenotype and is most frequently measured by RNA-sequencing (RNA-seq). Therefore, an ultimate goal is to perturb every gene and measure changes in the transcriptome. However, this remains challenging, especially in intact organisms due to different experimental and computational challenges. Here, we present ‘Worm Perturb-Seq...

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Literature Corpus work: 99edad39-acb7-5e7f-9c27-afd0e73102eb
DOI: 10.1101/2025.02.02.636107

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