Article
Melanocortin 1 receptor genotype: an important determinant of the damage response of melanocytes to ultraviolet radiation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Oct 2010
Kadekaro Ana Luisa, Leachman Sancy, Kavanagh Renny J, Swope Viki, Cassidy Pamela, Supp Dorothy, Sartor Maureen, Schwemberger Sandy, Babcock George, Wakamatsu Kazumasa, Ito Shosuke, Koshoffer Amy, Boissy Raymond E, Manga Prashiela, Sturm Richard A, Abdel-Malek Zalfa A
Abstract excerpt
The melanocortin 1 receptor gene is a main determinant of human pigmentation, and a melanoma susceptibility gene, because its variants that are strongly associated with red hair color increase melanoma risk. To test experimentally the association between melanocortin 1 receptor genotype and melan...
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