Article
High transcript level of FLT3 associated with high risk of relapse in pediatric acute myeloid leukemia.
Journal of Korean medical science - 1 Jun 2010
Kang Hyoung Jin, Lee Ji Won, Kho Sang Hyeok, Kim Min Jeong, Seo Young Jin, Kim Hyery, Shin Hee Young, Ahn Hyo Seop
Abstract excerpt
Identification of prognostic factors and risk-based post-remission therapy was proposed to improve the outcomes of acute myeloid leukemia (AML) and a mutation of FLT3 has been reported to be a risk factor, especially for pediatric patients. Recently, FLT3 expression level was implicated to have prognostic significance in adults, but little is known for childhood AML. To define the prognostic significance,...
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