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Article

Prognostic significance of FLT3 mutational status and expression levels in MLL-AF4+ and MLL-germline acute lymphoblastic leukemia.

Leukemia - 1 Nov 2012

Chillón M C, Gómez-Casares M T, López-Jorge C E, Rodriguez-Medina C, Molines A, Sarasquete M E, Alcoceba M, Miguel J D G-S, Bueno C, Montes R, Ramos F, Rodríguez J N, Giraldo P, Ramírez M, García-Delgado R, Fuster J L, González-Díaz M, Menendez P

Abstract excerpt

There is barely any information about the prognostic significance of FLT3 expression and mutational status in cytogenetically distinct subgroups of acute lymphoblastic leukemia (ALL). We analyzed the presence of FLT3-tyrosine kinase domain (TKD) and FLT3-internal tandem duplication (ITD) mutation...

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Source

Identifiers

PMID: 22705992
DOI: 10.1038/leu.2012.161

Genes

FLT3
BCR
ETV6
PBX1
RUNX1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22705992-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Prognostic significance of FLT3 mutational status and expression levels in MLL-AF4+ and MLL-germline acute lymphoblastic leukemia.PMID 22705992Read ↗

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