Article
Molecular involvement and prognostic importance of fms-like tyrosine kinase 3 in acute myeloid leukemia.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2012
Shahab Sadaf, Shamsi Tahirs, Ahmed Nuzhat
Abstract excerpt
AML (Acute myeloid leukemia) is a form of blood cancer where growth of myeloid cells occurs in the bone marrow. The prognosis is poor in general for many reasons. One is the presence of leukaemia-specific recognition markers such as FLT3 (fms-like tyrosine kinase 3). Another name of FLT3 is stem cell tyrosine kinase-1 (STK1), which is known to take part in proliferation, differentiation and apoptosis of...
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