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Article

Prognostic significance of FLT3 mutations in pediatric non-promyelocytic acute myeloid leukemia.

Leukemia research - 1 Jun 2005

Kang Hyoung Jin, Hong Seung-Hee, Kim In Hoo, Park Byung-Kiu, Han Kyou Sup, Cho Han Ik, Shin Hee Young, Ahn Hyo Seop

Abstract excerpt

FLT3 is a receptor tyrosine kinase involved in the survival of hematopoietic stem cells, and mutations of FLT3 have been reported to be of prognostic significance. This is the first study of FLT3 mutations in pediatric non-promyelocytic AML patients that received the same treatment scheme in single institute. FLT3 internal tandem duplication of the juxtamembrane domain (FLT3/ITD) and a point mutation in the...

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Source

Identifiers

PMID: 15863200
DOI: 10.1016/j.leukres.2004.11.006

Genes

FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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