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Article

Biologic and clinical significance of the FLT3 transcript level in acute myeloid leukemia.

Blood - 1 Mar 2004

Ozeki Kazutaka, Kiyoi Hitoshi, Hirose Yuka, Iwai Masanori, Ninomiya Manabu, Kodera Yoshihisa, Miyawaki Shuichi, Kuriyama Kazutaka, Shimazaki Chihiro, Akiyama Hideki, Nishimura Miki, Motoji Toshiko, Shinagawa Katsuji, Takeshita Akihiro, Ueda Ryuzo, Ohno Ryuzo, Emi Nobuhiko, Naoe Tomoki

Abstract excerpt

Although FLT3 mutations are essentially found in myeloid-lineage leukemia cells, a high level of FLT3 expression was recently observed in MLL gene-rearranged acute lymphoblastic leukemia without FLT3 mutations. Here, we analyzed the biologic and clinical significance of the FLT3 transcript level in comparison with several gene alterations in 181 de novo acute myeloid leukemia (AML) cases. The mean expression...

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Source

Identifiers

PMID: 14604973
DOI: 10.1182/blood-2003-06-1845

Genes

FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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