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Article

Regulation of vacuolar proton-translocating ATPase activity and assembly by extracellular pH.

The Journal of biological chemistry - 30 Jul 2010

Diakov Theodore T, Kane Patricia M

Abstract excerpt

Vacuolar proton-translocating ATPases (V-ATPases) are responsible for organelle acidification in all eukaryotic cells. The yeast V-ATPase, known to be regulated by reversible disassembly in response to glucose deprivation, was recently reported to be regulated by extracellular pH as well (Padilla-López, S., and Pearce, D. A. (2006) J. Biol. Chem. 281, 10273-10280). Consistent with those results, we find 57%...

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Identifiers

PMID: 20511227
DOI: 10.1074/jbc.M110.110122
PMCID: PMC2911326

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