Article
Physical interaction between aldolase and vacuolar H+-ATPase is essential for the assembly and activity of the proton pump.
The Journal of biological chemistry - 24 Aug 2007
Lu Ming, Ammar David, Ives Harlan, Albrecht Fred, Gluck Stephen L
Abstract excerpt
Vacuolar proton-translocating ATPases (V-ATPases) are a family of highly conserved proton pumps that couple hydrolysis of cytosolic ATP to proton transport out of the cytosol. Although V-ATPases are involved in a number of cellular processes, how the proton pumps are regulated under physiological conditions is not well understood. We have reported that the glycolytic enzyme aldolase mediates V-ATPase assembly and...
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