Article
Job Sharing in the Endomembrane System: Vacuolar Acidification Requires the Combined Activity of V-ATPase and V-PPase.
The Plant cell - 1 Dec 2015
Kriegel Anne, Andrés Zaida, Medzihradszky Anna, Krüger Falco, Scholl Stefan, Delang Simon, Patir-Nebioglu M Görkem, Gute Gezahegn, Yang Haibing, Murphy Angus S, Peer Wendy Ann, Pfeiffer Anne, Krebs Melanie, Lohmann Jan U, Schumacher Karin
Abstract excerpt
The presence of a large central vacuole is one of the hallmarks of a prototypical plant cell, and the multiple functions of this compartment require massive fluxes of molecules across its limiting membrane, the tonoplast. Transport is assumed to be energized by the membrane potential and the proton gradient established by the combined activity of two proton pumps, the vacuolar H(+)-pyrophosphatase (V-PPase) and...
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