Article
Chromophore formation in DsRed occurs by a branched pathway.
Journal of the American Chemical Society - 23 Jun 2010
Strack Rita L, Strongin Daniel E, Mets Laurens, Glick Benjamin S, Keenan Robert J
Abstract excerpt
Like GFP, the fluorescent protein DsRed has a chromophore that forms autocatalytically within the folded protein, but the mechanism of DsRed chromophore formation has been unclear. It was proposed that an initial oxidation generates a green chromophore, and that a final oxidation yields the red chromophore. However, this model does not adequately explain why a mature DsRed sample contains a mixture of green and...
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