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Article

Microsatellite polymorphism in promoter of heme oxygenase-1 gene is associated with susceptibility to coronary artery disease in type 2 diabetic patients.

Human genetics - 1 Jul 2002

Chen Ying-Hwa, Lin Shing-Jong, Lin Ming-Wei, Tsai Hui-Ling, Kuo San-San, Chen Jaw-Wen, Charng Min-Ji, Wu Tao-Cheng, Chen Lung-Ching, Ding Yu-An, Pan Wen-Harn, Jou Yuh-Shan, Chau Lee-Young

Abstract excerpt

Heme oxygenase is a rate-limiting enzyme in heme degradation, leading to the generation of free iron, biliverdin, and carbon monoxide. Induction of heme oxygenase-1 is implicated in the antioxidant defense mechanism and can modulate vascular function. To test the association of microsatellite polymorphism in the promoter region of human HO-1 gene with the risk of coronary artery disease (CAD) in type 2 diabetic...

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Coronary Artery Disease
Diabetes Mellitus, Type 2
Heme Oxygenase-1
Heme Oxygenase (Decyclizing)

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Muscle, Smooth, Vascular

Thiobarbituric Acid Reactive Substances

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PMID: 12136229
DOI: 10.1007/s00439-002-0769-4

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CAD

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Microsatellite polymorphism in promoter of heme oxygenase-1 gene is associated with susceptibility to coronary artery disease in type 2 diabetic patients.PMID 12136229Read ↗

Heme oxygenase-1 gene promoter polymorphism is associated with coronary artery disease in Japanese patients with coronary risk factors.Semantic proximity Read ↗

Serum bilirubin and ferritin levels link heme oxygenase-1 gene promoter polymorphism and susceptibility to coronary artery disease in diabetic patients.Semantic proximity Read ↗

Short (GT) ( n ) repeats in heme oxygenase-1 gene promoter are associated with lower risk of coronary heart disease in subjects with high levels of oxidative stress.Semantic proximity Read ↗

Association between heme oxygenase-1 gene promoter polymorphisms and type 2 diabetes in a Chinese population.Semantic proximity Read ↗

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Association between heme oxygenase 1 gene promoter polymorphisms and susceptibility to coronary artery disease: a HuGE review and meta-analysis.Semantic proximity Read ↗

Association Between Heme Oxygenase-1 Promoter Polymorphisms and the Development of Albuminuria in Type 2 Diabetes: A Case-Control Study.Semantic proximity Read ↗

Shorter GT repeat polymorphism in the heme oxygenase-1 gene promoter has protective effect on ischemic stroke in dyslipidemia patients.Semantic proximity Read ↗

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Subjects with coronary artery disease and reduced ejection fraction have longer (GT)n repeats in the heme-oxygenase 1 gene promoter.Semantic proximity Read ↗

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