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Article

Microsatellite polymorphism in heme oxygenase-1 gene promoter is associated with susceptibility to oxidant-induced apoptosis in lymphoblastoid cell lines.

Blood - 1 Sept 2003

Hirai Hisao, Kubo Hiroshi, Yamaya Mutsuo, Nakayama Katsutoshi, Numasaki Muneo, Kobayashi Seiichi, Suzuki Satoshi, Shibahara Shigeki, Sasaki Hidetada

Abstract excerpt

Heme oxygenase-1 (HO-1) confers cytoprotection against oxidative stress. A (GT)n dinucleotide repeat in the 5'-flanking region of human HO-1 gene shows length polymorphism, which was classified into S (< 27 GT), M (27-32 GT), and L alleles (>/= 33 GT). Polymorphism in the HO-1 gene promoter was shown to be associated with susceptibility to pulmonary emphysema and restenosis after angioplasty. However, the...

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Identifiers

PMID: 12730098
DOI: 10.1182/blood-2002-12-3733

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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