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Article

The effect of a promoter polymorphism in the heme oxygenase-1 gene on the risk of ischaemic cerebrovascular events: the influence of other vascular risk factors.

Thrombosis research - 1 Jan 2004

Funk Marion, Endler Georg, Schillinger Martin, Mustafa Stefan, Hsieh Kety, Exner Markus, Lalouschek Wolfgang, Mannhalter Christine, Wagner Oswald

Abstract excerpt

Heme oxygenase-1 (HO-1) has been demonstrated to exert potent anti-oxidant and anti-inflammatory effects in the context of atherosclerotic vascular disease, and therefore was referred to as a potential vascular protective factor. A (GT)n dinucleotide repeat polymorphism in the HO-1 promoter has been shown to modulate HO-1 gene expression. Short (<25) GT repeats were associated with HO-1 up-regulation, and...

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Identifiers

PMID: 15140586
DOI: 10.1016/j.thromres.2004.03.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The effect of a promoter polymorphism in the heme oxygenase-1 gene on the risk of ischaemic cerebrovascular events: the influence of other vascular risk factors.PMID 15140586Read ↗

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