Article
DNA repair under heat: DNA polymerase λ modulates heat stress-induced mutagenesis in plants.
The Plant cell - 3 Apr 2026
Wootan Clair M, Lutterman John, Springer Nathan, Xu Xiaosa, Zhang Feng
Abstract excerpt
Mutation rates often rise under environmental stress, a process known as stress-induced mutagenesis. Among abiotic factors, heat stress is a potent driver that elevates mutation rates and enhances genetic variation, yet the underlying mechanisms in eukaryotes remain unclear. Here, we investigated how heat stress influences DNA repair and mutagenesis both locally and globally in Arabidopsis thaliana using...
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