Article
Heritability of vasculopathy, autoimmune disease, and fibrosis in systemic sclerosis: a population-based study.
Arthritis and rheumatism - 1 Jul 2010
Frech Tracy, Khanna Dinesh, Markewitz Boaz, Mineau Geraldine, Pimentel Richard, Sawitzke Allen
Abstract excerpt
OBJECTIVE: To investigate the familiality of systemic sclerosis (SSc) in relation to Raynaud's phenomenon (RP) (a marker of vasculopathy), other autoimmune inflammatory disease, and fibrotic interstitial lung disease (ILD). METHODS: A genealogic resource, the Utah Population Database (UPDB), was used to test heritability of RP, other autoimmune disease, and ILD. Diseases were defined by International...
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