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The Evolving Landscape of Systemic Sclerosis Pathogenesis: From Foundational Mechanisms to Organ-Specific Modifiers

2025-03-26

Abstract excerpt

Systemic sclerosis (SSc) is a multifaceted autoimmune disease in which the complex interplay of genetic predisposition and environmental factors triggers aberrant immune responses, ultimately leading to vasculopathy and fibrosis. This review offers a com-prehensive overview of current perspectives on SSc pathogenesis, integrating classical concepts with recent breakthroughs enabled by advanced analytical technique...

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Literature Corpus work
bc4a69e1-d22b-54b5-9816-9d2c9a784410
DOI
10.20944/preprints202503.1958.v1
Open publication

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