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Permanently Blocked Stem Cells Derived From Breast Cancer Cell Lines

7 Apr 2010

Abstract excerpt

Cancer stem cells (CSCs) are thought to be resistant to standard chemotherapeutic drugs and the inimical conditions of the tumor microenvironment. Obtaining CSCs in sufficient quantities and maintaining their undifferentiated state have been major hurdles to their further characterization and to the identification of new pharmaceuticals that preferentially target these cells. We describe here the tagging of...

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PMID: 20506227
DOI: 10.1002/stem.424

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