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Targeting breast cancer stem cells

17 Jun 2010

Abstract excerpt

The cancer stem cell (CSC) hypothesis postulates that tumors are maintained by a self-renewing CSC population that is also capable of differentiating into non-self-renewing cell populations that constitute the bulk of the tumor. Although, the CSC hypothesis does not directly address the cell of origin of cancer, it is postulated that tissue-resident stem or progenitor cells are the most common targets of...

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PMID: 20599450
DOI: 10.1016/j.molonc.2010.06.005

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