Article
Breast cancer stem cells: current advances and clinical implications.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2015
Luo Ming, Clouthier Shawn G, Deol Yadwinder, Liu Suling, Nagrath Sunitha, Azizi Ebrahim, Wicha Max S
Abstract excerpt
There is substantial evidence that many cancers, including breast cancer, are driven by a population of cells that display stem cell properties. These cells, termed cancer stem cells (CSCs) or tumor initiating cells, not only drive tumor initiation and growth but also mediate tumor metastasis and therapeutic resistance. In this chapter, we summarize current advances in CSC research with a major focus on breast...
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