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Breast cancer stem cells: A review of their characteristics and the agents that affect them

11 Jan 2021

Abstract excerpt

The evolving concept that cancer stem cells (CSCs) are the driving element in cancer development, evolution and heterogeneity, has overridden the previous model of a tumor consisting of cells all with similar sequentially acquired mutations and a similar potential for renewal, invasion and metastasis. This paradigm shift has focused attention on therapeutically targeting CSCs directly as a means of eradicating...

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PMID: 33428807
DOI: 10.1002/mc.23277

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