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Cancer Stem Cells and Radiotherapy: New Insights Into Tumor Radioresistance

19 Dec 2006

Abstract excerpt

Solid tumors are histologically heterogeneous and include tumor cells, stroma, inflammatory infiltrates, and vascular structures. Furthermore, it has long been recognized that subpopulations of cancer cells exist within the tumors that resemble the developmental hierarchy of the normal tissue from which the tumor arose. In recent years, the cancer stem cell model of tumorigenesis has received increasing...

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PMID: 17179471
DOI: 10.1093/jnci/djj505

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