Article
Association of DISC1 gene with schizophrenia in families from two distinct French and Algerian populations.
Psychiatric genetics - 1 Dec 2010
Lepagnol-Bestel Aude-Marie, Dubertret Caroline, Benmessaoud Dalila, Simonneau Michel, Adès Jean, Kacha Farid, Hamdani Nora, Gorwood Philip, Ramoz Nicolas
Abstract excerpt
OBJECTIVE: The Disrupted-in-Schizophrenia-1 (DISC1) gene is a promising genetic risk factor for major mental illnesses, especially schizophrenia. Several variants encompassing the DISC1 gene have been associated with schizophrenia and specific clinical features. Negative results were nevertheless observed, stratification biases, heterogeneity of the analyzed samples and low statistical power being potentially...
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