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Article

NF1 inactivation in adult acute myelogenous leukemia.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Aug 2010

Parkin Brian, Ouillette Peter, Wang Yin, Liu Yan, Wright Whitney, Roulston Diane, Purkayastha Anjali, Dressel Amanda, Karp Judith, Bockenstedt Paula, Al-Zoubi Ammar, Talpaz Moshe, Kujawski Lisa, Liu Yang, Shedden Kerby, Shakhan Sajid, Li Cheng, Erba Harry, Malek Sami N

Abstract excerpt

PURPOSE: This study was conducted to identify novel genes with importance to the biology of adult acute myelogenous leukemia (AML). EXPERIMENTAL DESIGN: We analyzed DNA from highly purified AML blasts and paired buccal cells from 95 patients for recurrent genomic microdeletions using ultra-high density Affymetrix single nucleotide polymorphism 6.0 array-based genomic profiling. RESULTS: Through fine mapping of...

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Identifiers

PMID: 20505189
DOI: 10.1158/1078-0432.CCR-09-2639
PMCID: PMC2921448

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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