Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome wide molecular analysis of minimally differentiated acute myeloid leukemia.

Haematologica - 1 Nov 2009

Silva Fernando P G, Almeida Inês, Morolli Bruno, Brouwer-Mandema Geeske, Wessels Hans, Vossen Rolf, Vrieling Harry, Marijt Erik W A, Valk Peter J M, Kluin-Nelemans Hanneke C, Sperr Wolfgang R, Ludwig Wolf-Dieter, Giphart-Gassler Micheline

Abstract excerpt

BACKGROUND: Minimally differentiated acute myeloid leukemia is heterogeneous in karyotype and is defined by immature morphological and molecular characteristics. This originally French-American-British classification is still used in the new World Health Organization classification when other criteria are not met. Apart from RUNX1 mutation, no characteristic molecular aberrations are recognized. DESIGN AND...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Cell Differentiation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Cohort Studies

Share to Core Binding Factor Alpha 2 Subunit

Share to Genome, Human

Share to Karyotyping

Share to Leukemia, Myeloid, Acute

Source

Open in PubMed Open full text

Identifiers

PMID: 19773259
DOI: 10.3324/haematol.2009.009324
PMCID: PMC2770965

Genes

RUNX1
FLT3
JAK2
PTPN11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome wide molecular analysis of minimally differentiated acute myeloid leukemia.PMID 19773259Read ↗

Multi-omics analysis of pediatric minimally differentiated acute myeloid leukemia reveals RUNX1-driven stemness and chemoresistance.Semantic proximity Read ↗

Acute Myeloid Leukemia With Recurrent Genetic Abnormalities Other Than Translocations.Semantic proximity Read ↗

Spectrum and prognostic relevance of driver gene mutations in acute myeloid leukemia.Semantic proximity Read ↗

NF1 inactivation in adult acute myelogenous leukemia.Semantic proximity Read ↗

Gene expression profiling of minimally differentiated acute myeloid leukemia: M0 is a distinct entity subdivided by RUNX1 mutation status.Semantic proximity Read ↗

Frequency and Clinicopathologic Features of RUNX1 Mutations in Patients With Acute Myeloid Leukemia Not Otherwise Specified.Semantic proximity Read ↗

The new provisional WHO entity ‘RUNX1 mutated AML’ shows specific genetics but no prognostic influence of dysplasiaSemantic proximity Read ↗

Genome profiling of chronic myelomonocytic leukemia: frequent alterations of RAS and RUNX1 genes.Semantic proximity Read ↗

Gene mutation patterns in patients with minimally differentiated acute myeloid leukemia.Semantic proximity Read ↗

Accurate and Sensitive Analysis of Minimal Residual Disease in Acute Myeloid Leukemia Using Deep Sequencing of Single Nucleotide VariationsSemantic proximity Read ↗

Beyond morphologySemantic proximity Read ↗

Molecular methods used for detection of minimal residual disease following hematopoietic stem cell transplantation in myeloid disorders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.