Pigment epithelium-derived factor expression in colorectal cancer patients.

doi:10.3109/07357901003735675

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Article

Pigment epithelium-derived factor expression in colorectal cancer patients.

Cancer investigation - 1 Oct 2010

Wågsäter Dick, Löfgren Sture, Zar Niklas, Hugander Anders, Dimberg Jan

Abstract excerpt

Pigment epithelium-derived factor (PEDF) is a potent inhibitor of angiogenesis and has been proposed to be a tumor suppressor in a variety of tumors. Limited reports exist of PEDF in colorectal cancer (CRC). We noted a 55% lower plasma level (p < .001) of PEDF in the CRC patient group (1.6 μg/mL) than in of a healthy control group (3.6 μg/mL). A single nucleotide polymorphism (rs1136287, T>C) was screened. In the...

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PMID: 20504225
DOI: 10.3109/07357901003735675

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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