Article
Downregulation of pigment epithelium-derived factor is associated with increased epithelial-mesenchymal transition in bladder cancer.
Panminerva medica - 1 Mar 2017
Dong Bin B, Yan Jia S, Yan Yang Y, Xie Tian C, Xu Liang, Hu Guang H, Xu Yun F, Liu Min
Abstract excerpt
BACKGROUND: Pigment epithelium-derived factor (PEDF) has been reported to inhibit angiogenesis in bladder cancer, but whether it modulates epithelial-mesenchymal transition (EMT) remains unknown. METHODS: We have included 68 samples of non-muscle invasive bladder cancer in this study. Immunohistochemistry was performed in all sample sections for expressions of PEDF, SNAI2, Vimentin and E-cadherin, which were...
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