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Article

The forkhead-box family of transcription factors: key molecular players in colorectal cancer pathogenesis

8 Jan 2019

Abstract excerpt

Colorectal cancer (CRC) is the third most commonly occurring cancer worldwide and the fourth most frequent cause of death having an oncological origin. It has been found that transcription factors (TF) dysregulation, leading to the significant expression modifications of genes, is a widely distributed phenomenon regarding human malignant neoplasias. These changes are key determinants regarding tumour's behaviour...

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PMID: 30621735
DOI: 10.1186/s12943-019-0938-x

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